Replicas of human organs would permit progress within the therapy of …

The researcher of the Regenerative Medicine Program of the Cima and the Cell Therapy Area of ​​the University of Navarra Clinic, Manuel Mazo, has affirmed that the potential of producing small replicas of human organs with stem cells and bioengineering methods, referred to as organoids, “opens a wide range of research opportunities for a better approach to diseases, from Covid-19 to rare diseases “.

Mazo, who has reported that lately there was a “revolution” within the area of Regenerative Medicine, made these statements on the symposium ‘Vanguard Regenerative Medicine’, organized final Thursday by the Cima and the Clínica Universidad de Navarre.

This occasion, which was attended by greater than 100 researchers, college students and most people in face-to-face and digital codecs, had a scientific and an informative half through which the challenges and the most recent technological and bioengineering advances utilized to well being have been addressed.

As reported by the University of Navarra Clinic in a press launch, the periods got by scientific consultants and representatives of the nationwide and worldwide biotechnology sector.


Regenerative Medicine consists of repairing or changing a broken organ. “One of its main challenges is to solve the shortage of organs available for transplantation, an effective treatment, but one that fails to meet the demand,” says Xabier Aranguren, researcher from the Cima Regenerative Medicine Program and speaker on the informative session of the symposium. .

According to the most recent report ‘Transplant Newsletter’ from the National Transplant Organization and the Council of Europe, in 2020 lower than 30% of the true wants for organ transplants have been coated within the European Union.

To reply to this problem, explains the researcher, “we seek to generate human organs on a real scale from stem cells with a technique called blastocyst complementation. This procedure allows the formation of a complete and healthy organ of one species within a different species. “.

“We have managed to develop chimeras and the heart in rat and mouse models and we are working to try to achieve human-pig chimeras, which will allow us to advance the development of human organs from stem cells,” says Aranguren.

The day was framed inside the analysis in personalised regenerative medication of the Cima and the Clinic by way of the CARDIOPATCH (Interreg Sudoe), LGMed (Interreg Poctefa) and BRAVE (Horizon 2020) tasks.

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